Ryzodeg 100IU/ml FlexTouch is a prefilled insulin pen that combines two types of insulin in one: a long-acting basal insulin (insulin degludec) and a rapid-acting mealtime insulin (insulin aspart). It’s a 70/30 co-formulation 70% basal + 30% rapid designed to help you cover background insulin needs and the rise in blood sugar from meals with a single, easy-to-use pen. If your healthcare provider has prescribed Ryzodeg, this pen is made to keep daily life a bit simpler and more steady.
Why people choose Ryzodeg FlexTouch
- Dual-action in one pen basal coverage + mealtime coverage in a single injection.
- Typically taken once daily with your main meal (your prescriber may adjust this).
- Consistent dosing in 1‑unit increments.
- Prefilled, ready to use no vials, no mixing.
- Clear solution (not cloudy), so it’s easy to visually check before you inject.
Who it’s for
Ryzodeg 100IU/ml FlexTouch is used to improve blood sugar control in people with diabetes who need both background and mealtime insulin. Your clinician will decide if this co-formulation is right for you. It’s not for treating diabetic ketoacidosis, and it’s not for use in an insulin pump.
How to use Ryzodeg 100IU/ml FlexTouch
Always follow the plan your healthcare provider gives you. Here’s the simple, everyday version:
- When to inject: Usually once daily with your main meal. If your provider tells you to split it into two doses with two main meals, do that. The with food part matters.
- Where to inject: Belly (abdomen), thigh, or upper arm. Rotate sites to avoid lumps or irritation.
- Pen setup:
- Attach a new, single-use pen needle.
- Prime the pen (usually 2 units) until you see insulin at the needle tip.
- Dial your dose, inject, count slowly as shown in the leaflet, then remove the needle.
- Do not mix Ryzodeg with other insulins, do not transfer it into a syringe, and do not use it in a pump.
- Don’t share your pen with anyone even if you switch needles.
Storage and handling
- Unopened pens: Keep refrigerated (36°F to 46°F). Don’t freeze. If it freezes, toss it.
- In-use pen: Keep at room temperature (generally below 86°F), away from heat and sunlight. Use within the in-use time listed in the manufacturer’s leaflet (many people use an opened pen for up to 28 days). Keep the cap on when not in use.
- Never store with a needle attached. Needles are single-use swap them every injection.
Possible side effects
Not a complete list, but here are the big ones to watch for:
- Low blood sugar (hypoglycemia) Shakiness, sweating, fast heartbeat, hunger, confusion. Treat quickly as directed by your care team.
- Injection site reactions Redness, itching, or mild swelling.
- Lipodystrophy or skin thickening at injection sites rotate locations to help prevent this.
- Swelling in hands/feet or slight weight gain.
- Rare but serious allergic reactions. Get medical help if you notice hives, trouble breathing, or swelling of the face/tongue.
- Low potassium (hypokalemia) can happen in some cases your provider monitors this if needed.
What’s in the box
- Ryzodeg 100IU/ml FlexTouch prefilled insulin pens (each pen contains 3 mL = 300 units).
- Most pharmacies supply a carton with multiple pens (often 5), but pack sizes can vary by location.
- Pen needles are typically not included. Use compatible single-use pen needles as directed by your pharmacist or prescriber.
Important safety notes
- Not for DKA or for insulin pumps.
- Alcohol can affect your blood sugar use caution.
- Certain medications (like steroids or some antibiotics) may raise or lower your blood sugar tell your provider what you take.
- If you’re sick, traveling, pregnant, or planning intense exercise, your dose may need tweaks. Ask your care team first.
- Drive or operate machines carefully if you’ve had a recent low or you’re unsure where your sugar sits.
Frequently Asked Questions
Q: What exactly is Ryzodeg 100IU/ml FlexTouch?
A: It’s a prefilled insulin pen that combines long-acting insulin degludec (70%) with rapid-acting insulin aspart (30%) in one solution to manage blood sugar throughout the day and at mealtime.
Q: When should I take it?
A: Usually once daily with your main meal. Your prescriber might adjust the timing or number of doses based on your needs.
Q: Can I use Ryzodeg in an insulin pump?
A: No. Ryzodeg is for subcutaneous injection by pen only. Don’t mix it with other insulins and don’t transfer it into a syringe.
Q: What if I miss a dose?
A: Follow your provider’s instructions. In general, take it with a meal when you remember. If it’s close to your next dose, don’t double up. Check your blood sugar and call your prescriber if you’re not sure.
Q: How long does one pen last?
A: Each pen has 300 units. If you use 30 units a day, that’s roughly 10 days. Your daily dose will determine how long it lasts.
Q: Do I need to prime the pen?
A: Yes. Prime per the instructions (commonly 2 units) before each injection to make sure the pen is ready and the dose is accurate.
Q: What needles work with FlexTouch?
A: Most standard single-use pen needles that fit FlexTouch are fine. Your pharmacist can recommend sizes (length/gauge) that match your comfort and technique.
Q: How should I store an in-use pen?
A: Keep it at room temperature, away from heat and direct sun. Cap on, needle off. Follow the leaflet for the exact in-use time window.
Q: Can I change my dose on my own?
A: Only if your provider has given you a titration plan. If not, don’t adjust it yourself.
Q: Is it normal to see cloudy insulin?
A: Ryzodeg should be clear and colorless. If it looks cloudy, gritty, or colored, or if the pen is damaged, do not use it.


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